Research Interests

I develop mathematical, computational, and conceptual models to study natural selection and the evolution of organismal design. My work makes testable predictions on topics ranging from microbial life history to sociality to cancer. My study of particular topics leads to syntheses of natural selection, robustness in relation to biological design, and the commonly observed patterns that emerge from information flow and scale.

For a technical narrative summary, download my 2018 pdf research statement. For a gentler summary that covers a broader range of topics, click on the links below.

General Approach (last update 2014)

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Specific puzzles

Empirical and conceptual syntheses

Life history in relation to conflict and cooperation

Other conceptual syntheses

Recent Projects

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Virulence and mechanisms of pathogenesis

Microbial life history

Natural selection

Information, probability, and the common patterns of nature

Epidemiology and evolution of infectious disease

Cancer, age-specific disease, and somatic genomics

Robustness and regulatory networks

Past Projects

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Sex allocation and sociality

Genomic conflict

Host-parasite dynamics

Virulence, symbiosis, and sociality

Other topics